html_url,issue_url,id,node_id,user,created_at,updated_at,author_association,body,reactions,issue,performed_via_github_app https://github.com/dogsheep/genome-to-sqlite/issues/1#issuecomment-544646516,https://api.github.com/repos/dogsheep/genome-to-sqlite/issues/1,544646516,MDEyOklzc3VlQ29tbWVudDU0NDY0NjUxNg==,9599,2019-10-21T18:30:14Z,2019-10-21T18:30:14Z,MEMBER,"Thanks to help from Dr. Laura Cantino at Science Hack Day San Francisco I've been able to pull together this query: ```sql select rsid, genotype, case genotype when 'AA' then 'brown eye color, 80% of the time' when 'AG' then 'brown eye color' when 'GG' then 'blue eye color, 99% of the time' end as interpretation from genome where rsid = 'rs12913832' ``` See also https://www.snpedia.com/index.php/Rs12913832 - in particular this table: ","{""total_count"": 0, ""+1"": 0, ""-1"": 0, ""laugh"": 0, ""hooray"": 0, ""confused"": 0, ""heart"": 0, ""rocket"": 0, ""eyes"": 0}",496415321, https://github.com/dogsheep/genome-to-sqlite/issues/1#issuecomment-544648863,https://api.github.com/repos/dogsheep/genome-to-sqlite/issues/1,544648863,MDEyOklzc3VlQ29tbWVudDU0NDY0ODg2Mw==,9599,2019-10-21T18:36:03Z,2019-10-21T18:36:03Z,MEMBER," ","{""total_count"": 0, ""+1"": 0, ""-1"": 0, ""laugh"": 0, ""hooray"": 0, ""confused"": 0, ""heart"": 0, ""rocket"": 0, ""eyes"": 0}",496415321, https://github.com/dogsheep/genome-to-sqlite/issues/1#issuecomment-765495861,https://api.github.com/repos/dogsheep/genome-to-sqlite/issues/1,765495861,MDEyOklzc3VlQ29tbWVudDc2NTQ5NTg2MQ==,25372415,2021-01-22T15:44:00Z,2021-01-22T15:44:00Z,NONE,"Risk of autoimmune disorders: https://www.snpedia.com/index.php/Genotype ``` select rsid, genotype, case genotype when 'AA' then '2x risk of rheumatoid arthritis and other autoimmune diseases' when 'GG' then 'Normal risk for autoimmune disorders' end as interpretation from genome where rsid = 'rs2476601' ```","{""total_count"": 0, ""+1"": 0, ""-1"": 0, ""laugh"": 0, ""hooray"": 0, ""confused"": 0, ""heart"": 0, ""rocket"": 0, ""eyes"": 0}",496415321, https://github.com/dogsheep/genome-to-sqlite/issues/1#issuecomment-765498984,https://api.github.com/repos/dogsheep/genome-to-sqlite/issues/1,765498984,MDEyOklzc3VlQ29tbWVudDc2NTQ5ODk4NA==,25372415,2021-01-22T15:48:25Z,2021-01-22T15:49:33Z,NONE,"The ""Warrior Gene"" https://www.snpedia.com/index.php/Rs4680 ``` select rsid, genotype, case genotype when 'AA' then '(worrier) advantage in memory and attention tasks' when 'AG' then 'Intermediate dopamine levels, other effects' when 'GG' then '(warrior) multiple associations, see details' end as interpretation from genome where rsid = 'rs4680' ``` ","{""total_count"": 0, ""+1"": 0, ""-1"": 0, ""laugh"": 0, ""hooray"": 0, ""confused"": 0, ""heart"": 0, ""rocket"": 0, ""eyes"": 0}",496415321, https://github.com/dogsheep/genome-to-sqlite/issues/1#issuecomment-765502845,https://api.github.com/repos/dogsheep/genome-to-sqlite/issues/1,765502845,MDEyOklzc3VlQ29tbWVudDc2NTUwMjg0NQ==,25372415,2021-01-22T15:53:19Z,2021-01-22T15:53:19Z,NONE,"rs7903146 Influences risk of Type-2 diabetes https://www.snpedia.com/index.php/Rs7903146 ``` select rsid, genotype, case genotype when 'CC' then 'Normal (lower) risk of Type 2 Diabetes and Gestational Diabetes.' when 'CT' then '1.4x increased risk for diabetes (and perhaps colon cancer).' when 'TT' then '2x increased risk for Type-2 diabetes' end as interpretation from genome where rsid = 'rs7903146' ```","{""total_count"": 0, ""+1"": 0, ""-1"": 0, ""laugh"": 0, ""hooray"": 0, ""confused"": 0, ""heart"": 0, ""rocket"": 0, ""eyes"": 0}",496415321, https://github.com/dogsheep/genome-to-sqlite/issues/1#issuecomment-765506901,https://api.github.com/repos/dogsheep/genome-to-sqlite/issues/1,765506901,MDEyOklzc3VlQ29tbWVudDc2NTUwNjkwMQ==,25372415,2021-01-22T15:58:41Z,2021-01-22T15:58:58Z,NONE,"Both rs10757274 and rs2383206 can both indicate higher risks of heart disease https://www.snpedia.com/index.php/Rs2383206 ``` select rsid, genotype, case genotype when 'AA' then 'Normal' when 'AG' then '~1.2x increased risk for heart disease' when 'GG' then '~1.3x increased risk for heart disease' end as interpretation from genome where rsid = 'rs10757274' ``` ``` select rsid, genotype, case genotype when 'AA' then 'Normal' when 'AG' then '1.4x increased risk for heart disease' when 'GG' then '1.7x increased risk for heart disease' end as interpretation from genome where rsid = 'rs2383206' ```","{""total_count"": 0, ""+1"": 0, ""-1"": 0, ""laugh"": 0, ""hooray"": 0, ""confused"": 0, ""heart"": 0, ""rocket"": 0, ""eyes"": 0}",496415321, https://github.com/dogsheep/genome-to-sqlite/issues/1#issuecomment-765523517,https://api.github.com/repos/dogsheep/genome-to-sqlite/issues/1,765523517,MDEyOklzc3VlQ29tbWVudDc2NTUyMzUxNw==,25372415,2021-01-22T16:20:25Z,2021-01-22T16:20:25Z,NONE,"rs53576: the oxytocin receptor (OXTR) gene ``` select rsid, genotype, case genotype when 'AA' then 'Lack of empathy?' when 'AG' then 'Lack of empathy?' when 'GG' then 'Optimistic and empathetic; handle stress well' end as interpretation from genome where rsid = 'rs53576' ```","{""total_count"": 0, ""+1"": 0, ""-1"": 0, ""laugh"": 0, ""hooray"": 0, ""confused"": 0, ""heart"": 0, ""rocket"": 0, ""eyes"": 0}",496415321, https://github.com/dogsheep/genome-to-sqlite/issues/1#issuecomment-765525338,https://api.github.com/repos/dogsheep/genome-to-sqlite/issues/1,765525338,MDEyOklzc3VlQ29tbWVudDc2NTUyNTMzOA==,25372415,2021-01-22T16:22:44Z,2021-01-22T16:22:44Z,NONE,"rs1333049 associated with coronary artery disease https://www.snpedia.com/index.php/Rs1333049 ``` select rsid, genotype, case genotype when 'CC' then '1.9x increased risk for coronary artery disease' when 'CG' then '1.5x increased risk for CAD' when 'GG' then 'normal' end as interpretation from genome where rsid = 'rs1333049' ```","{""total_count"": 0, ""+1"": 0, ""-1"": 0, ""laugh"": 0, ""hooray"": 0, ""confused"": 0, ""heart"": 0, ""rocket"": 0, ""eyes"": 0}",496415321, https://github.com/dogsheep/genome-to-sqlite/issues/1#issuecomment-831004775,https://api.github.com/repos/dogsheep/genome-to-sqlite/issues/1,831004775,MDEyOklzc3VlQ29tbWVudDgzMTAwNDc3NQ==,25372415,2021-05-03T03:46:23Z,2021-05-03T03:46:23Z,NONE,"RS1800955 is related to novelty seeking and ADHD https://www.snpedia.com/index.php/Rs1800955 `select rsid, genotype, case genotype when 'CC' then 'increased susceptibility to novelty seeking' when 'CT' then 'increased susceptibility to novelty seeking' when 'TT' then 'normal' end as interpretation from genome where rsid = 'rs1800955'`","{""total_count"": 0, ""+1"": 0, ""-1"": 0, ""laugh"": 0, ""hooray"": 0, ""confused"": 0, ""heart"": 0, ""rocket"": 0, ""eyes"": 0}",496415321,