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  • cobiadigital · 6 ✖

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id html_url issue_url node_id user created_at updated_at ▲ author_association body reactions issue performed_via_github_app
765525338 https://github.com/dogsheep/genome-to-sqlite/issues/1#issuecomment-765525338 https://api.github.com/repos/dogsheep/genome-to-sqlite/issues/1 MDEyOklzc3VlQ29tbWVudDc2NTUyNTMzOA== cobiadigital 25372415 2021-01-22T16:22:44Z 2021-01-22T16:22:44Z NONE

rs1333049 associated with coronary artery disease
https://www.snpedia.com/index.php/Rs1333049

select rsid, genotype, case genotype
  when 'CC' then '1.9x increased risk for coronary artery disease'
  when 'CG' then '1.5x increased risk for CAD'
  when 'GG' then 'normal'
end as interpretation from genome where rsid = 'rs1333049'

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 Figure out some interesting example SQL queries 496415321  
765523517 https://github.com/dogsheep/genome-to-sqlite/issues/1#issuecomment-765523517 https://api.github.com/repos/dogsheep/genome-to-sqlite/issues/1 MDEyOklzc3VlQ29tbWVudDc2NTUyMzUxNw== cobiadigital 25372415 2021-01-22T16:20:25Z 2021-01-22T16:20:25Z NONE

rs53576: the oxytocin receptor (OXTR) gene

select rsid, genotype, case genotype
  when 'AA' then 'Lack of empathy?'
  when 'AG' then 'Lack of empathy?'
  when 'GG' then 'Optimistic and empathetic; handle stress well'
end as interpretation from genome where rsid = 'rs53576'

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 Figure out some interesting example SQL queries 496415321  
765506901 https://github.com/dogsheep/genome-to-sqlite/issues/1#issuecomment-765506901 https://api.github.com/repos/dogsheep/genome-to-sqlite/issues/1 MDEyOklzc3VlQ29tbWVudDc2NTUwNjkwMQ== cobiadigital 25372415 2021-01-22T15:58:41Z 2021-01-22T15:58:58Z NONE

Both rs10757274 and rs2383206 can both indicate higher risks of heart disease
https://www.snpedia.com/index.php/Rs2383206

select rsid, genotype, case genotype
  when 'AA' then 'Normal'
  when 'AG' then '~1.2x increased risk for heart disease'
  when 'GG' then '~1.3x increased risk for heart disease'
end as interpretation from genome where rsid = 'rs10757274'

select rsid, genotype, case genotype
  when 'AA' then 'Normal'
  when 'AG' then '1.4x increased risk for heart disease'
  when 'GG' then '1.7x increased risk for heart disease'
end as interpretation from genome where rsid = 'rs2383206'

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 Figure out some interesting example SQL queries 496415321  
765502845 https://github.com/dogsheep/genome-to-sqlite/issues/1#issuecomment-765502845 https://api.github.com/repos/dogsheep/genome-to-sqlite/issues/1 MDEyOklzc3VlQ29tbWVudDc2NTUwMjg0NQ== cobiadigital 25372415 2021-01-22T15:53:19Z 2021-01-22T15:53:19Z NONE

rs7903146 Influences risk of Type-2 diabetes
https://www.snpedia.com/index.php/Rs7903146

select rsid, genotype, case genotype
  when 'CC' then 'Normal (lower) risk of Type 2 Diabetes and Gestational Diabetes.'
  when 'CT' then '1.4x increased risk for diabetes (and perhaps colon cancer).'
  when 'TT' then '2x increased risk for Type-2 diabetes'
end as interpretation from genome where rsid = 'rs7903146'

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 Figure out some interesting example SQL queries 496415321  
765498984 https://github.com/dogsheep/genome-to-sqlite/issues/1#issuecomment-765498984 https://api.github.com/repos/dogsheep/genome-to-sqlite/issues/1 MDEyOklzc3VlQ29tbWVudDc2NTQ5ODk4NA== cobiadigital 25372415 2021-01-22T15:48:25Z 2021-01-22T15:49:33Z NONE

The "Warrior Gene" https://www.snpedia.com/index.php/Rs4680

select rsid, genotype, case genotype
  when 'AA' then '(worrier) advantage in memory and attention tasks'
  when 'AG' then 'Intermediate dopamine levels, other effects'
  when 'GG' then '(warrior) multiple associations, see details'
end as interpretation from genome where rsid = 'rs4680'

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 Figure out some interesting example SQL queries 496415321  
765495861 https://github.com/dogsheep/genome-to-sqlite/issues/1#issuecomment-765495861 https://api.github.com/repos/dogsheep/genome-to-sqlite/issues/1 MDEyOklzc3VlQ29tbWVudDc2NTQ5NTg2MQ== cobiadigital 25372415 2021-01-22T15:44:00Z 2021-01-22T15:44:00Z NONE

Risk of autoimmune disorders: https://www.snpedia.com/index.php/Genotype

select rsid, genotype, case genotype
  when 'AA' then '2x risk of rheumatoid arthritis and other autoimmune diseases'
  when 'GG' then 'Normal risk for autoimmune disorders'
end as interpretation from genome where rsid = 'rs2476601'

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 Figure out some interesting example SQL queries 496415321  

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CREATE TABLE [issue_comments] (
   [html_url] TEXT,
   [issue_url] TEXT,
   [id] INTEGER PRIMARY KEY,
   [node_id] TEXT,
   [user] INTEGER REFERENCES [users]([id]),
   [created_at] TEXT,
   [updated_at] TEXT,
   [author_association] TEXT,
   [body] TEXT,
   [reactions] TEXT,
   [issue] INTEGER REFERENCES [issues]([id])
, [performed_via_github_app] TEXT);
CREATE INDEX [idx_issue_comments_issue]
                ON [issue_comments] ([issue]);
CREATE INDEX [idx_issue_comments_user]
                ON [issue_comments] ([user]);